Company Filing History:
Years Active: 2025
Title: Innovations in Lipid Nanoparticle Technology by Seo Hyeon Bae
Introduction
Seo Hyeon Bae is an accomplished inventor based in Gimhae-si, South Korea. He has made significant contributions to the field of pharmaceutical compositions, particularly in the development of lipid nanoparticles for delivering nucleic acid drugs. His innovative work aims to enhance the stability and delivery of these drugs in vivo.
Latest Patents
Seo Hyeon Bae holds a patent for a pharmaceutical composition of lipid nanoparticles designed for delivering nucleic acid drugs containing a trehalose derivative and a novel structure-maintaining lipid compound. This patent discloses a unique composition of lipid nanoparticles that stabilizes nucleic acid drugs and improves their delivery. The lipid nanoparticles include various types of nucleic acid drugs, such as mRNA-based vaccines, RNA for immune boosters, miRNA, siRNA, pDNA, and antisense ODN. The lipid component consists of a trehalose-based lipid, an ionizable lipid, a phospholipid, a PEG-lipid, and a structure-maintaining lipid. This innovative structure-maintaining lipid can replace commonly used cholesterol with derivatives of lithocholic acid, glycyrrhetinic acid, or diosgenin. The versatility of these lipid nanoparticles allows them to be utilized as either vaccines or therapeutic agents, depending on the nucleic acid drug employed.
Career Highlights
Seo Hyeon Bae is currently associated with Sml Biopharm Co., Ltd., where he continues to advance his research in lipid nanoparticle technology. His work has garnered attention for its potential applications in the pharmaceutical industry, particularly in vaccine development and gene therapy.
Collaborations
Seo Hyeon Bae collaborates with notable colleagues, including Eun Kyoung Bang and Gyo Chang Keum. Their combined expertise contributes to the innovative research and development efforts at Sml Biopharm Co., Ltd.
Conclusion
Seo Hyeon Bae's contributions to lipid nanoparticle technology represent a significant advancement in the delivery of nucleic acid drugs. His innovative approach has the potential to enhance therapeutic outcomes in various medical applications.