Company Filing History:
Years Active: 1999
Title: Seema Sharma: Innovator in Insulin Production Research
Introduction: Seema Sharma is a notable inventor based in La Jolla, California. With a keen focus on the characterization of compounds that stimulate STF-1, her work has made significant contributions to the field of diabetes research.
Latest Patents: Seema Sharma holds a patent titled "Methods for the characterization of compounds which stimulate STF-1." This innovative method allows for testing various compounds that may induce STF-1 transcription. By isolating pancreatic islet cells that express the STF-1/lacZ fusion gene, she measures the effects of different compounds on STF-1 expression. A colorimetric assay quantifies LacZ activity in both control and treated cells, enabling the efficient screening of several compounds for STF-1 inducing properties. Additionally, her invention includes a method using the STF-1 promoter to mark insulin-producing pancreatic islet cells in vivo, utilizing green fluorescent protein (GFP) as an indicator. The introduction of the STF-1 green fluorescent protein transgene into pigs facilitates the rapid recovery of insulin-producing cells from the pancreas.
Career Highlights: Seema Sharma is associated with the Research Development Foundation, where she contributes to advancements in biomedical research. Her innovative approach to characterizing compounds has positioned her at the forefront of research aimed at improving treatments for diabetes.
Collaborations: Throughout her career, Seema has collaborated with esteemed colleagues, including Marc R Montminy, to enhance the impact of her research and drive forward the understanding of insulin production. Together, they work towards creating innovative solutions to improve diabetes treatment and patient outcomes.
Conclusion: Seema Sharma's groundbreaking work in the characterization of compounds related to STF-1 has established her as an influential figure in biomedical research. Her patent reflects a significant advancement in the field, showcasing her commitment to innovation and collaboration in the fight against diabetes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.