Sanju Sharma

Title: Sanju Sharma: Innovator in Cell Growth Treatment

Introduction

Sanju Sharma is a notable inventor based in Berkeley, CA, who has made significant contributions to the field of biotechnology. His work primarily focuses on methods and compositions for treating abnormal cell growth, which is crucial in addressing various pathological conditions.

Latest Patents

Sanju Sharma holds a patent titled "Methods and compositions for treating abnormal cell growth related to unwanted guanine nucleotide exchange factor activity." This patent describes innovative methods that affect the GTPase activity of members of the Ras superfamily, particularly Rac. The compositions include guanine nucleotide exchange factors that modulate GTPase activity, preferably in the presence of GEF enhancers. Notably, exemplary guanine nucleotide exchange factors such as Rac-GEF and Tiam-1 are encoded by specific nucleic acid sequences detailed in the patent. These methods also encompass uses for the guanine nucleotide exchange factors and nucleic acid sequences, including screening for ligands that recognize Rac-GEF and regulators of Rac-GEF activity.

Career Highlights

Sanju Sharma is currently associated with Onyx Pharmaceuticals, Inc., where he continues to advance his research and development efforts. His work has the potential to impact the treatment of conditions associated with the Ras superfamily GTPase, including Rac.

Collaborations

Throughout his career, Sanju has collaborated with esteemed colleagues such as Gideon Bollag and Anne M Crompton. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.

Conclusion

Sanju Sharma's contributions to the field of biotechnology, particularly in the treatment of abnormal cell growth, highlight his role as an influential inventor. His patent and ongoing work at Onyx Pharmaceuticals, Inc. demonstrate his commitment to advancing medical science and improving patient outcomes.