Company Filing History:
Years Active: 2006
Title: Innovations of Sandra Weller in Viral Recombinases
Introduction
Sandra Weller is a prominent inventor based in Unionville, CT (US). She has made significant contributions to the field of virology, particularly in the development of viral recombinases. Her work has implications for cloning, cell treatment, and the production of transgenic animals.
Latest Patents
Sandra Weller holds a patent for "Viral recombinases, related articles, and methods of use thereof." This patent describes a Herpes simplex virus (HSV) recombinase that comprises a purified or isolated alkaline nuclease and a single-stranded DNA binding protein. In HSV-1, the alkaline nuclease is identified as the UL12 protein, while the single-stranded DNA binding protein is the ICP8 protein. The HSV recombinase can be purified from an in vitro expression system or expressed in appropriate vectors where the DNAs encoding the polypeptides are operatively linked to expression control sequences. The methods of use for the HSV recombinase include cloning, treating cells and organisms, and producing transgenic animals. Additionally, the HSV recombinase can be packaged in a kit useful for cloning.
Career Highlights
Sandra Weller is affiliated with the University of Connecticut, where she continues her research and development in virology. Her innovative work has garnered attention in the scientific community, contributing to advancements in genetic engineering and therapeutic applications.
Collaborations
Some of her notable coworkers include Richard S. Myers and Nina Bacher Reuven. Their collaborative efforts have further enhanced the research output and innovation in their respective fields.
Conclusion
Sandra Weller's contributions to the field of viral recombinases exemplify the impact of innovative research in biotechnology. Her patent and ongoing work at the University of Connecticut highlight the importance of scientific advancements in medicine and genetic engineering.