Company Filing History:
Years Active: 2013
Title: Innovations by Sachin S Talathi in Epileptogenesis Detection
Introduction
Sachin S Talathi is an accomplished inventor based in Gainesville, Florida. He has made significant contributions to the field of neuroscience, particularly in understanding epileptogenesis. His innovative work focuses on detecting neuronal excitation and inhibition in the brain, which is crucial for developing therapeutic measures for epilepsy.
Latest Patents
Sachin S Talathi holds a patent for a method and system for detecting epileptogenesis. This patent outlines a process where neuronal activity in the hippocampal CA1 network is monitored during a latent period. The method identifies biomarkers such as a sustained increase in the firing rate of excitatory postsynaptic field activity, coupled with a decrease in inhibitory postsynaptic field activity. The findings reveal that both excitatory and inhibitory CA1 field activity firing rates exhibit a circadian rhythm that changes during epileptogenesis. Additionally, a change in the circadian rhythm of core body temperature is noted as a significant biomarker. The therapeutic measures proposed can include thermal, chemical, or electrical modulation.
Career Highlights
Sachin S Talathi is associated with the University of Florida Research Foundation, Incorporated. His work has been instrumental in advancing the understanding of epilepsy and its underlying mechanisms. His research has the potential to lead to innovative therapeutic approaches for managing this condition.
Collaborations
Sachin has collaborated with notable colleagues, including Dong-Uk Hwang and William Lawrence Ditto. Their combined expertise contributes to the depth and breadth of research in the field of neuroscience.
Conclusion
Sachin S Talathi's innovative work in detecting epileptogenesis represents a significant advancement in neuroscience. His contributions have the potential to improve therapeutic strategies for epilepsy, showcasing the importance of research in understanding complex neurological conditions.