Location History:
- Gaithersburg, MD (US) (2009)
- Frederick, MD (US) (2011)
Company Filing History:
Years Active: 2009-2011
Title: Ruth Barratt: Innovator in Biopharmaceutical Production
Introduction
Ruth Barratt is a notable inventor based in Frederick, MD (US), recognized for her contributions to the field of biopharmaceuticals. With a total of two patents to her name, she has made significant strides in utilizing crustaceans and rotifers as production systems for therapeutic proteins. Her innovative approaches have the potential to revolutionize the way biopharmaceuticals are produced.
Latest Patents
Ruth Barratt's latest patents include "Crustaceans as production systems for therapeutic proteins" and "Transfected shrimp as production systems for therapeutic proteins." Both patents describe a method where a crustacean or rotifer is infected with a recombinant infectious virus that expresses a protein exogenous to the virus. Importantly, the genome of the crustacean or rotifer remains unaltered. The transcription of a gene inserted into the recombinant virus genome is driven by crustacean, rotifer, insect, or viral promoters, allowing the virus to replicate in the cell cytoplasm. The infected organisms can be provided directly to humans or non-human animals, or after production and harvest, purified recombinant proteins or polypeptides can be obtained. This production system enables the rapid and inexpensive generation of large quantities of biopharmaceuticals.
Career Highlights
Ruth Barratt is currently associated with Advanced Bionutrition Corporation, where she continues to develop her innovative ideas. Her work focuses on enhancing the efficiency and cost-effectiveness of biopharmaceutical production through the use of living organisms.
Collaborations
Ruth has collaborated with notable colleagues, including F C Thomas Allnutt and Robert Bullis, contributing to the advancement of her research and the development of her patents.
Conclusion
Ruth Barratt's innovative work in the field of biopharmaceutical production showcases her commitment to advancing medical science. Her patents reflect a significant leap forward in the use of biological systems for therapeutic applications.