Changsha, China

Ruifang Wu


 

Average Co-Inventor Count = 4.0

ph-index = 1


Company Filing History:


Years Active: 2023

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1 patent (USPTO):Explore Patents

Title: Innovations in Inflammatory Skin Disease Treatment by Ruifang Wu

Introduction

Ruifang Wu is a notable inventor based in Changsha, China. He has made significant contributions to the field of dermatology, particularly in the treatment of inflammatory skin diseases. His innovative approach focuses on the application of microRNA-210 inhibitors, which has the potential to revolutionize therapeutic strategies in this area.

Latest Patents

Ruifang Wu holds a patent titled "Application of microRNA-210 inhibitor in preparation of drugs for treating inflammatory skin diseases." This patent outlines methods for utilizing a microRNA-210 inhibitor to develop drugs aimed at treating various inflammatory skin conditions. Through extensive experimentation, Wu has demonstrated that inhibiting microRNA-210 expression can significantly enhance the expression of its target gene, STAT6. This process inhibits the proliferation and chemokine CCL20 secretion of keratinocytes, which further reduces T cell migration towards skin lesions and inhibits the differentiation of T1 and T17 cells. His research indicates that microRNA-210 knockout and the intradermal injection of a microRNA-210 inhibitor can effectively mitigate skin inflammation in mice, providing a new pathophysiological mechanism for treating inflammatory skin diseases.

Career Highlights

Ruifang Wu is affiliated with The Second Xiangya Hospital of Central South University, where he conducts his research and clinical work. His dedication to advancing medical science is evident in his innovative research and the practical applications of his findings.

Collaborations

Wu collaborates with esteemed colleagues, including Qianjin Lu and Ming Zhao, who contribute to his research efforts and help advance the understanding of inflammatory skin diseases.

Conclusion

Ruifang Wu's work in the field of inflammatory skin disease treatment showcases the potential of microRNA-210 inhibitors as a novel therapeutic strategy. His contributions are paving the way for new drug development and improved patient outcomes in dermatology.

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