Company Filing History:
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1 out of 2 
1 out of 1 Years Active: 2017-2022
Title: Innovations of Rui Pedro Romero Amandi De Sousa
Introduction
Rui Pedro Romero Amandi De Sousa is a notable inventor based in Matosinhos, Portugal. He has made significant contributions to the field of tissue engineering and regenerative medicine. With a total of 3 patents to his name, his work focuses on the development of innovative hydrogels that have the potential to revolutionize medical applications.
Latest Patents
One of his latest patents involves the creation of gellan gum hydrogels, which are designed for in vitro cell culture and tissue engineering applications. These hydrogels can be utilized alone or in combination with live cells and biomolecules for applications in both humans and animals. The chemical modification of gellan gum with selected ion-chelating substituents results in novel hydrogels that possess tunable physicochemical and biological properties. These modified gellan gum hydrogels offer several advantages over existing systems, including enhanced solubility, versatility in ionic crosslinking, ease of formulation, injectability, and improved adhesiveness to biological tissues. They also maintain the viability of encapsulated cells during extended culture periods and promote the expression of healthy extracellular matrix markers.
Another significant patent focuses on gellan gum-based hydrogels for promoting chondrogenic, osteogenic, and adipogenic differentiation of human mesenchymal stem cells, with a preference for osteogenic differentiation. This patent also relates to a composition intended for use in bone, cartilage, and soft tissue engineering, particularly in bone applications.
Career Highlights
Rui Pedro has worked with various organizations that are at the forefront of tissue engineering and regenerative medicine. Notable among these is the Association for the Advancement of Tissue Engineering and Cell Based Technologies and Therapies (a4tec) and Stemmatters, a company specializing in biotechnology and regenerative medicine.
Collaborations
Throughout his career, Rui Pedro has collaborated with esteemed colleagues, including Cristina Correia and David Alexander Learmonth. These collaborations have further enriched his research and innovations in the field.
Conclusion
Rui Pedro Romero Amandi De Sousa is a pioneering inventor whose work in gellan gum hydrogels is paving the way for advancements in tissue engineering and regenerative medicine. His contributions are significant and hold promise for future medical applications.