Ru Cao

Title: Innovations of Ru Cao in Histone Methyltransferase Research

Introduction

Ru Cao is an accomplished inventor based in Chapel Hill, NC (US). She has made significant contributions to the field of biochemistry, particularly in the study of histone methyltransferase complexes. Her work has implications for cancer treatment and understanding epigenetic regulation.

Latest Patents

Ru Cao holds a patent for a reconstituted histone methyltransferase complex and methods of identifying modulators thereof. The patent describes a reconstituted complex that includes EED, EZH2, and SUZ12, which exhibits histone methyltransferase (HMTase) activity for lysine 27 of histone H3 (H3-K27). The invention also encompasses methods for producing the complex, identifying compounds that inhibit its HMTase activity, and discovering candidate compounds for cancer treatment. Additionally, reagents and kits that include the reconstituted complex are provided.

Career Highlights

Ru Cao is affiliated with the University of North Carolina at Chapel Hill, where she conducts her research. Her innovative work has led to advancements in understanding the mechanisms of histone modification and its role in gene regulation.

Collaborations

Ru Cao has collaborated with notable researchers in her field, including Yi Zhang and Hengbin Wang. These collaborations have further enhanced the impact of her research and contributed to the advancement of knowledge in histone methyltransferase activity.

Conclusion

Ru Cao's contributions to the field of histone methyltransferase research are noteworthy. Her patent and ongoing research efforts hold promise for future developments in cancer treatment and epigenetic studies.