Ronald Sayler

Title: The Innovations of Ronald Sayler

Introduction

Ronald Sayler is an accomplished inventor based in Farmington, Arkansas. He has made significant contributions to agricultural biotechnology, particularly in the development of transgenic crops. His work focuses on enhancing plant resistance to fungal infections, which is crucial for food safety and crop yield.

Latest Patents

One of Ronald Sayler's notable patents is for transgenic corn that expresses the antifungal peptide AGM182. This innovation addresses the threat posed by the opportunistic fungus that infects maize and other fatty acid-rich crops, producing harmful aflatoxins. In vitro studies demonstrated a five-fold increase in antifungal activity of AGM182 compared to tachyplesin1. The transgenic maize plants were developed through mediated transformation, and PCR products confirmed the successful integration of the AGM182 gene. Furthermore, RT-PCR analysis of maize RNA confirmed the presence of AGM182 transcripts. A maize kernel screening assay using a highly aflatoxigenic strain showed up to 72% reduction in fungal growth in the transgenic AGM182 seeds compared to isogenic negative control seeds.

Career Highlights

Throughout his career, Ronald Sayler has worked with various organizations, including Genvor Inc. and the United States of America, as represented by the Secretary of Agriculture. His expertise in agricultural biotechnology has positioned him as a key figure in the field, contributing to advancements that enhance food safety and crop resilience.

Collaborations

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Conclusion

Ronald Sayler's innovative work in developing transgenic corn with antifungal properties showcases his commitment to improving agricultural practices and ensuring food safety. His contributions are vital in the ongoing battle against crop diseases and the production of safe food supplies.