Romano Di Fabio

Title: Innovations of Romano Di Fabio in Pharmaceutical Synthesis

Introduction

Romano Di Fabio is a notable inventor based in Milan, Italy. He has made significant contributions to the field of pharmaceutical synthesis, particularly through his innovative processes for preparing key intermediates. With a total of 2 patents to his name, Di Fabio's work is instrumental in the development of active pharmaceutical ingredients.

Latest Patents

Di Fabio's latest patents include a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction. This invention focuses on the enzymatic reduction of beta-amino ketones, leading to the creation of novel synthesis intermediates. These intermediates are crucial for the preparation of active pharmaceutical ingredients, including vilanterol and its salts. Another significant patent involves a process for the preparation of a novel umeclidinium synthesis intermediate. This invention not only details the synthesis of a versatile intermediate but also includes reference standards for detecting impurity traces during the preparation of umeclidinium.

Career Highlights

Romano Di Fabio is associated with Olon S.p.a., a company known for its commitment to pharmaceutical innovation. His work at Olon has allowed him to focus on developing processes that enhance the efficiency and effectiveness of drug synthesis.

Collaborations

Di Fabio has collaborated with esteemed colleagues such as Corrado Colli and Giorgio Bertolini. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and advancements in pharmaceutical research.

Conclusion

Romano Di Fabio's contributions to pharmaceutical synthesis through his innovative patents highlight his role as a key inventor in the industry. His work continues to influence the development of important pharmaceutical compounds, showcasing the impact of innovation in healthcare.