Robert Edmon Guisinger

Title: Robert Edmon Guisinger: Innovator in Pharmaceutical Microencapsulation

Introduction

Robert Edmon Guisinger, based in Dayton, OH, has made significant contributions to the field of pharmaceuticals through his innovative research and development. With a total of two patents to his name, Guisinger has focused on enhancing drug delivery methods, specifically through microencapsulation techniques.

Latest Patents

Guisinger's latest patent is a procedure for encapsulating ibuprofen. This invention is centered around the preparation of individual taste-masked, high bioavailability, high payload microcapsules. These microcapsules are developed through microencapsulation of water-insoluble NSAID (non-steroidal anti-inflammatory drug) materials while ensuring a substantial absence of microcapsule agglomerates.

The taste-masked microcapsules are notable for containing approximately 83% or more of the NSAID drug material, allowing for the formulation into chewable tablets and liquid aqueous suspensions for medicinal use. The microencapsulating polymer wall materials include both cellulose acetate phthalate and gelatin. Importantly, parameters such as pH control, the addition of Hofmeister (lyotropic) salts, and the microencapsulation process with a liquid phase of the encapsulating materials play critical roles in achieving the desired properties of these innovative microcapsules.

Career Highlights

Guisinger has dedicated his career to advancing drug formulation techniques, particularly at Eurand America, Inc., where he has made strides in pharmaceutical development. His inventions have the potential to improve patient compliance and medication effectiveness through enhanced bioavailability.

Collaborations

During his career, Guisinger has collaborated with notable professionals, including his coworker Sambasiva Rao Ghanta. This teamwork has allowed for a rich exchange of ideas and advancements in the field of microencapsulation.

Conclusion

Robert Edmon Guisinger stands out as an inventive force in the pharmaceutical industry. His patents, specifically concerning the encapsulation of ibuprofen, can lead to significant advancements in drug formulation and patient care. As he continues his work at Eurand America, Inc., the impact of his innovations is sure to be felt within the medical community and beyond.