Robert Day

Title: The Innovative Contributions of Robert Day

Introduction

Robert Day is a notable inventor based in Ste-Dorothee, Canada. He has made significant contributions to the field of biochemistry, particularly in the study of pro-hormone convertases. His work has implications for understanding various biological processes and potential therapeutic applications.

Latest Patents

Robert Day holds a patent for a novel member of the subtilisin-kexin family, known as rPC7. This invention relates to a mammalian pro-hormone convertase isolated from rat. The rat spleen cDNA has been completely sequenced, and a shorter DNA sequence has been obtained for humans, corresponding to a portion of the catalytic region of a human pro-hormone convertase. PC7 distinguishes itself from other mammalian members of the subtilisin-kexin family, with a ubiquitous tissue distribution, particularly notable in lymphoid tissues. Its presence in LoVo cells, which cleave the HIV gp160 protein into active gp120/gp41 proteins, suggests that PC7 may serve as a maturation enzyme responsible for the conversion of HIV gp160 protein in target CD4+ cells.

Career Highlights

Robert Day is affiliated with the Clinical Research Institute of Montreal, where he continues to advance his research. His work has garnered attention for its potential impact on understanding HIV and other biological processes.

Collaborations

Throughout his career, Robert has collaborated with esteemed colleagues such as Nabil G Seidah and Michel Chretien. These collaborations have further enriched his research and contributed to the scientific community.

Conclusion

Robert Day's innovative work in the field of biochemistry, particularly with his patent on rPC7, highlights his contributions to science and medicine. His research continues to pave the way for advancements in understanding pro-hormone convertases and their applications.