Robert A Benoit

Title: The Innovations of Robert A. Benoit

Introduction

Robert A. Benoit is a notable inventor based in San Diego, California. He has made significant contributions to the field of biological studies, particularly through his innovative work on glycosylated analogs of somatostatin. His research has implications for enhancing the effectiveness of peptide analogs in medical applications.

Latest Patents

Benoit holds a patent for glycosylated analogs of somatostatin. This invention modifies somatostatin (SS) to incorporate a carbohydrate moiety in the peptide chain by linkage to either Asn, Ser, or Thr. The modified SS peptide analog may have a specific formula wherein R1 is preferably a hexose or amino-hexose, such as glucose or N-acetylglucosamine. The glycosomatostatins developed by Benoit exhibit an extended biological half-life compared to the parent peptide while maintaining substantially the same potency. This innovation allows for modifications and substitutions with respect to other amino acid residues in the chain, aimed at increasing the effectiveness of SS analogs.

Career Highlights

Benoit is affiliated with the Salk Institute for Biological Studies, where he conducts his research. His work has been instrumental in advancing the understanding of peptide modifications and their biological effects.

Collaborations

Benoit has collaborated with esteemed colleagues such as Roger C. Guillemin and Solange Lavielle, contributing to a rich environment of scientific inquiry and innovation.

Conclusion

Robert A. Benoit's contributions to the field of biological studies through his patent on glycosylated analogs of somatostatin highlight his role as an influential inventor. His work continues to impact the development of effective medical treatments.