Company Filing History:
Years Active: 1992-1999
Title: Richard Harris Wilson: Innovator in Recombinant DNA Technology
Introduction
Richard Harris Wilson is a notable inventor based in Glasgow, GB. He has made significant contributions to the field of biotechnology, particularly in recombinant DNA technology. With a total of 4 patents, Wilson's work has advanced the understanding and application of genetic engineering.
Latest Patents
Wilson's latest patents include innovative methods and vectors for recombinant DNA. One of his key inventions relates to vectors that are useful for transforming a lymphoid cell line to glutamine independence. These vectors comprise an active glutamine synthetase (GS) gene along with a heterologous gene of interest. The preferred embodiments of this invention feature vectors where the heterologous gene is expressed from a relatively strong promoter, while the GS gene is expressed from a relatively weak promoter. In one example, the heterologous gene is operatively linked to the hCMV-MIE promoter, and the GS gene is linked to the SV40 early region promoter. Another significant patent involves recombinant DNA sequences that encode the complete amino acid sequence of a glutamine synthetase, along with vectors containing these sequences. These inventions serve as dominant selectable markers for co-amplification of non-selected genes and in transforming host cell lines to glutamine independence.
Career Highlights
Throughout his career, Wilson has worked with esteemed organizations such as the University of Glasgow and Celltech Therapeutics Limited. His work in these institutions has allowed him to explore and develop groundbreaking technologies in the field of genetic engineering.
Collaborations
Wilson has collaborated with notable colleagues, including Christopher Robert Bebbington and Geoffrey Thomas Yarranton. These partnerships have contributed to the advancement of his research and innovations.
Conclusion
Richard Harris Wilson is a prominent figure in the realm of recombinant DNA technology, with a focus on developing vectors and methods that enhance genetic engineering applications. His contributions continue to influence the field and pave the way for future innovations.