Richard G Cotton

Title: Innovations and Contributions of Richard G Cotton

Introduction

Richard G Cotton is a notable inventor based in Melbourne, Australia. He has made significant contributions to the field of molecular biology, particularly in the detection of mutations in nucleic acids. With a total of three patents to his name, Cotton's work has advanced the methodologies used in genetic research and diagnostics.

Latest Patents

Cotton's latest patents include innovative methods for detecting mutations and mismatches in nucleic acids. One of his patents, titled "Detection of mutation by resolvase cleavage," discloses methods for identifying mutations in isolated test nucleic acids by forming heteroduplexes with homologous control DNA. This method utilizes bacteriophage T4 endonuclease VII, a resolvase that recognizes single base pair mismatches within the heteroduplex. Another significant patent is "Detection of mismatches by resolvase cleavage using a magnetic bead." This method involves a series of steps to detect mismatches between two nucleic acids, utilizing magnetic beads and resolvase for analysis.

Career Highlights

Throughout his career, Richard G Cotton has worked with various companies, including Variagenics, Inc. and Avitech Diagnostics, Inc. His experience in these organizations has contributed to his expertise in molecular diagnostics and genetic research.

Collaborations

Cotton has collaborated with notable colleagues such as Rima Youil and Borries W Kemper. These collaborations have likely enriched his research and development efforts in the field.

Conclusion

Richard G Cotton's innovative patents and career achievements highlight his significant contributions to molecular biology and genetic diagnostics. His work continues to influence the methodologies used in detecting genetic mutations and mismatches.