Company Filing History:
Years Active: 2023-2024
Title: Innovations of Randall Mastrangelo in Cancer Genotyping
Introduction
Randall Mastrangelo is an accomplished inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of cancer research through his innovative patents. With a total of 2 patents, his work focuses on advanced methodologies for identifying specific mutations associated with various cancers.
Latest Patents
Mastrangelo's latest patents include a groundbreaking method for morphometric genotyping of cells in liquid biopsy using optical tomography. This classification training method is designed to train classifiers that can identify specific mutations, including driver mutations, associated with different types of cancer. The process begins with acquiring first cells from mutation cell lines that have a certain number of driver mutations. 3D image feature data from these cells is then identified. Furthermore, 3D cell imaging data is generated from both the first cells and other malignant cells, which includes individual cell images. A second set of 3D cell imaging data is created from a set of normal cells where driver mutations are expected to occur. This second set also includes individual cell images. The method employs supervised learning based on cell line status as ground truth to generate a classifier.
Career Highlights
Randall Mastrangelo is currently associated with Visiongate, Inc., where he continues to develop innovative solutions in the realm of cancer diagnostics. His work has been instrumental in advancing the understanding of cancer mutations and improving diagnostic accuracy.
Collaborations
Mastrangelo collaborates with notable colleagues, including Michael G Meyer and Daniel J Sussman, who contribute to the innovative research environment at Visiongate, Inc.
Conclusion
Randall Mastrangelo's contributions to cancer genotyping through his patents reflect his dedication to advancing medical technology. His innovative methods have the potential to significantly impact cancer diagnosis and treatment.