Company Filing History:
Years Active: 2004
Title: Innovating Vaccine Preservation: The Contributions of Ralph J Mancinelli
Introduction: Ralph J Mancinelli, an accomplished inventor based in Harleysville, Pennsylvania, has made significant contributions to the field of vaccine preservation. With a focus on innovative solutions, he holds a patent that introduces a novel combination of preservatives designed to enhance vaccine stability and efficacy.
Latest Patents: Mancinelli's sole patent revolves around preservatives for vaccines. His innovative formula consists of methyl and propyl parabens, benzyl alcohol, and 2-phenoxyethanol. These preservatives have demonstrated their capability to pass antimicrobial testing according to the standards set by the United States Pharmacopeia (USP), British Pharmacopoeia (BP), and European Pharmacopoeia (EP). The development involved incorporating L-histidine as a buffer to maintain a pH of 7.0, ensuring optimal conditions for vaccine preservation. Additionally, high-performance liquid chromatography (HPLC) methods were established to analyze both the preservatives and their degradation products, further ensuring the safety and effectiveness of vaccines.
Career Highlights: Ralph J Mancinelli is primarily associated with Merck & Company, Inc., a leading pharmaceutical company known for its contributions to healthcare through research and innovation. His work has not only advanced the preservation methods of vaccines but has also contributed to ensuring public health safety.
Collaborations: Throughout his career, Mancinelli has collaborated with esteemed colleagues, including Assunta S Ng and John P Hennessey. These partnerships underscore the importance of teamwork in driving innovation within the medical and pharmaceutical fields.
Conclusion: Ralph J Mancinelli's innovative work in developing preservatives for vaccines highlights the critical intersection of scientific research and public health. His patent stands as a testament to his commitment to enhancing vaccine preservation methods, ensuring that vaccines remain effective and safe for populations worldwide. Through his career at Merck & Company, Inc., Mancinelli continues to influence the landscape of vaccine innovation.