Company Filing History:
Years Active: 2015
Title: Rajesh Jayac Han Dran: Innovator in Immunosuppressant Activity Screening
Introduction
Rajesh Jayac Han Dran is a notable inventor based in Basel, Switzerland. He has made significant contributions to the field of immunology through his innovative research and patent work. His expertise lies in the identification of compounds that exhibit immunosuppressant activity, which has important implications for medical treatments.
Latest Patents
Rajesh holds a patent titled "Screening for compounds having immunosuppressant activity by testing impact on leukocyte-specific calcium fluxes." This invention relates to an assay designed to identify compounds that can block the Caflux in coronin 1 expressing cells and/or in coronin 1 negative cells. A candidate compound is recognized as having immunosuppressant activity if it specifically blocks the Caflux in coronin 1 expressing cells. The patent further describes upstream assays that measure the impact of candidate compounds on coronin 1 trimerization, as well as downstream assays that evaluate the effects on diacyl glycerol (DAG) generation, phosphatidylinositol-4,5-biphosphate (PIP) levels, inositol-1,4,5-triphosphate (InsP) generation, and nuclear factor of activated T cells (NFAT) nuclear localization.
Career Highlights
Rajesh is affiliated with the University of Basel, where he conducts his research and develops his innovative ideas. His work has garnered attention in the scientific community, particularly for its potential applications in immunology and therapeutic development.
Collaborations
Some of his notable coworkers include Jean Pieters and Philipp Mueller, who contribute to the collaborative research environment at the University of Basel.
Conclusion
Rajesh Jayac Han Dran is a prominent inventor whose work in immunosuppressant activity screening is paving the way for advancements in medical research. His contributions are vital for the development of new therapeutic strategies.