Raife Dilek Turan

Title: Raife Dilek Turan: Innovator in Hematopoietic Stem Cell Research

Introduction

Raife Dilek Turan is a notable inventor based in Istanbul, Turkey. She has made significant contributions to the field of hematopoietic stem cell research. Her innovative work focuses on the inhibition of MEIS proteins, which play a crucial role in the proliferation of these stem cells.

Latest Patents

Raife Dilek Turan holds a patent for a composition that inhibits MEIS proteins. This formulation is designed to easily pass through cell membranes and perform its activity within the cell. It can inhibit MEIS activity in a dose-dependent manner. The combination includes isolated cells, medium, growth factors, and MEISi inhibitors. The isolated cells are derived from mouse bone marrow, human bone marrow, and human umbilical cord blood. The medium has a pH value of 7.2 and contains bovine serum albumin, recombinant insulin, transferrin, 2-mercaptoethanol, and IMDM medium. The growth factors involved are hematopoietic stem cell factor SCF, fetus liver tyrosine kinase-3 ligand Flt3L, and thrombopoietin. The chemical formula of MEISi-1 is 4-[2-(benzylamino)-2-oxoethoxy]-N-(2,3-dimethylphenyl) benzamide, while MEISi-2 is represented by the formula 4-hydroxy-N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl] benzohydrazide.

Career Highlights

Throughout her career, Raife Dilek Turan has worked with esteemed institutions, including Yeditepe University. Her research has significantly advanced the understanding of hematopoietic stem cell proliferation and the role of MEIS proteins.

Collaborations

Raife has collaborated with Fatih Kocabas, who has contributed to her research endeavors.

Conclusion

Raife Dilek Turan's innovative work in the field of hematopoietic stem cell research highlights her dedication to advancing medical science. Her patent on inhibiting MEIS proteins represents a significant step forward in this important area of study.