Company Filing History:
Years Active: 1993-2008
Title: Raif S Geha: Innovator in Genetic Research
Introduction
Raif S Geha is a prominent inventor based in Belmont, MA (US), known for his significant contributions to genetic research. He holds a total of 10 patents, showcasing his innovative approach to addressing complex biological challenges. His work primarily focuses on the development of novel genetic tools and therapeutic methods.
Latest Patents
One of Geha's latest patents is related to WIP, a WASP-associated protein. This invention describes a novel gene and its product, WIP, which associates with WASP. The subject invention relates to the isolated WIP gene or cDNA and transgenic mammals that have the WIP gene disrupted in their genome. Additionally, the invention outlines methods for treating conditions or diseases where WIP and/or WASP DNA or protein is deficient or defective. This includes methods for altering or regulating WIP functions in mammals or their cells, particularly in lymphocytes. Another significant patent involves circular site-directed mutagenesis, which provides improved methods for introducing site-directed mutations into circular DNA molecules using mutagenic primer pairs. This method allows for the efficient recovery of double-stranded circular DNA containing desired mutations.
Career Highlights
Throughout his career, Raif S Geha has worked with notable organizations, including Children's Medical Center Corporation. His innovative research has led to advancements in genetic engineering and therapeutic applications, making a lasting impact in the field.
Collaborations
Geha has collaborated with esteemed colleagues such as John C Bauer and Dowain A Wright, contributing to a rich exchange of ideas and expertise in his research endeavors.
Conclusion
Raif S Geha's work exemplifies the spirit of innovation in genetic research, with his patents paving the way for new therapeutic strategies and genetic tools. His contributions continue to influence the scientific community and enhance our understanding of genetic functions.