Tirat Carmel, Israel

Rafi De Picciotto

USPTO Granted Patents = 5 

Average Co-Inventor Count = 3.0

ph-index = 2

Forward Citations = 11(Granted Patents)


Company Filing History:


Years Active: 2022-2025

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5 patents (USPTO):Explore Patents

Title: The Innovative Mind of Rafi De Picciotto

Introduction

Rafi De Picciotto, an accomplished inventor based in Tirat Carmel, Israel, has made significant contributions to the field of medical technology. With four patents to his name, De Picciotto's work primarily focuses on groundbreaking methods for manipulating the blood-brain barrier using ultrasound technology. His innovations have the potential to revolutionize treatments for various neurological conditions.

Latest Patents

Two of Rafi De Picciotto's latest patents showcase his expertise in ultrasound applications. The first patent, titled "Systems and methods for selective, targeted opening of the blood-brain barrier," outlines a technique that uses ultrasound sonication to temporarily disrupt the blood-brain barrier (BBB) for targeted therapeutic delivery. This system includes the storing of threshold values related to acoustic response levels and tissue response doses. By measuring these values and comparing them to stored thresholds, the ultrasound transducer can optimally operate to open the BBB for drug delivery.

The second patent, "Focused ultrasound system with optimized monitoring of cavitation," describes an innovative approach to generating an ultrasound focus at a target region and receiving signals using a multi-element ultrasound transducer. This technology involves acquiring multiple images to determine tissue characteristics and using those insights to fine-tune the ultrasound beam. This refinement enhances the system's ability to create a precise focus on the target region, improving both efficacy and safety in treatments.

Career Highlights

Rafi De Picciotto has worked with prominent companies in the medical technology sector, including Insightec and Insighten. At Insightec, he contributed to the development of focused ultrasound systems, further establishing his reputation as a leader in medical innovations. His career reflects a dedication to advancing techniques that bridge technology and healthcare.

Collaborations

Throughout his career, Rafi De Picciotto has collaborated with innovative minds such as Yoav Levy and Javier Grinfeld. These partnerships have played a crucial role in the development of his patents and have further propelled advancements in the field of ultrasound technology and its applications in medicine.

Conclusion

Rafi De Picciotto’s work exemplifies the spirit of innovation in medical technology. Through his latest patents and collaborative efforts, he is at the forefront of creating solutions that could significantly impact treatments for neurological conditions. As advancements continue to unfold, the implications of his inventions may lead to new standards in patient care and therapeutic delivery.

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