Company Filing History:
Years Active: 2020
Title: The Innovative Contributions of Raffaele Pilla to Neuroscience
Introduction
Raffaele Pilla, an inventor based in Tampa, FL, has made significant strides in the field of neuroscience through his innovative research. With one patent to his name, Pilla's work focuses on the therapeutic applications of ketone esters in treating various neurological conditions.
Latest Patents
Pilla's patent, titled "Use of ketone esters for prevention of CNS oxygen toxicity," highlights the potential of ketone esters in managing seizure disorders, Alzheimer’s disease, and malignant brain cancer. This invention underscores the synthesis of ketone esters derived from acetoacetate, which can include R,S-1,3-butanediol acetoacetate monoester and R,S-1,3-butanediol acetoacetate diester. His research illustrates how the administration of these ketone esters results in therapeutic ketosis and neuroprotection against seizures caused by CNS oxygen toxicity. Additionally, supplemental ketones have demonstrated a reduction in superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and Aβ-42, further supporting their therapeutic efficacy.
Career Highlights
Raffaele Pilla is affiliated with the University of South Florida, where he conducts his groundbreaking research. His work integrates innovative approaches to tackle complex neurological issues, making substantial contributions to both academic and therapeutic communities.
Collaborations
Pilla collaborates with fellow researchers Dominic Paul D’Agostino and Jay B. Dean, enhancing his research endeavors. Together, they bring diverse expertise to their studies, focusing on metabolic dysregulation and its implications for neurological health.
Conclusion
Raffaele Pilla's innovative research and patent reflect a promising avenue in the treatment of serious neurological conditions. His dedication to exploring the therapeutic applications of ketone esters positions him as a key figure in the quest for new treatments that may offer hope to those affected by seizure disorders, Alzheimer’s disease, and brain cancer.