Raffaele De Francesco

Title: Raffaele De Francesco: Innovator in Hepatitis C Research

Introduction

Raffaele De Francesco is a prominent inventor based in Rome, Italy. He has made significant contributions to the field of molecular biology and virology, particularly in the study of the hepatitis C virus (HCV). With a total of 5 patents to his name, his work has advanced the understanding and treatment of this viral infection.

Latest Patents

Among his latest patents is the invention titled "Hepatitis C virus replicons and replicon enhanced cells." This invention features nucleic acid containing one or more adaptive mutations that enhance HCV replicon activity. Additionally, it includes HCV replicon enhanced cells, which are cells with an increased ability to maintain an HCV replicon. Another notable patent is the "Method for identifying a HCV RNA-dependent RNA polymerase inhibitor." This invention relates to the molecular biology and virology of HCV, providing a method to reproduce in vitro the RNA-dependent RNA polymerase activity of HCV using sequences contained in the HCV NS5B protein.

Career Highlights

Raffaele has worked with esteemed organizations such as the Istituto di Ricerche di Biologia Molecolare P. Angeletti S.p.a. His research has been pivotal in developing methods and tools for studying HCV, contributing to the broader scientific community's understanding of viral infections.

Collaborations

Throughout his career, Raffaele has collaborated with notable colleagues, including Licia Tomei and Sven-Erik Behrens. These collaborations have enriched his research and expanded the impact of his inventions.

Conclusion

Raffaele De Francesco's innovative work in hepatitis C research has led to significant advancements in the field. His patents reflect a commitment to improving the understanding and treatment of viral infections. His contributions continue to influence the scientific community and pave the way for future research.