Radharani Duttagupta

Title: Radharani Duttagupta: Innovator in Biomarker Research

Introduction

Radharani Duttagupta is a prominent inventor based in Foster City, California. She has made significant contributions to the field of biomarker research, holding three patents that showcase her innovative spirit and dedication to advancing medical diagnostics.

Latest Patents

One of her latest patents is the "Viterbi decoder for microarray signal processing." This invention presents a system and method for region-based calling that utilizes a probability distribution of a phi-transformed logarithmic ratio. It determines a set of possible transition paths through markers and marker states, constructs a local evidence matrix for each marker, and generates a total per-marker value for each segment in a discrete region. Another notable patent is focused on "Circulating miRNA biomarker signatures." This patent discloses methods for diagnosing and surveilling complex multi-factorial disorders, such as cancer, by screening easily accessible biomarkers. It highlights the discovery of highly stable cell-free circulating nucleic acids (CNA) present as both RNA and DNA species in human blood and plasma. The correlations between tumor-associated genomic, epigenetic, and transcriptional changes and alterations in CNA levels are strong predictors of the utility of this biomarker class as clinical indicators.

Career Highlights

Throughout her career, Radharani has worked with notable companies, including Affymetrix, Inc. and Genisphere, LLC. Her work has significantly impacted the field of molecular diagnostics and cancer research.

Collaborations

Radharani has collaborated with esteemed colleagues, including Keith W. Jones and Robert C. Getts. Their combined expertise has contributed to the advancement of innovative solutions in biomarker research.

Conclusion

Radharani Duttagupta's contributions to the field of biomarker research through her patents and collaborations highlight her as a leading innovator. Her work continues to pave the way for advancements in medical diagnostics and cancer treatment.