Company Filing History:
Years Active: 2001
Title: Rachelle Crosbie: Innovator in Genetic Research
Introduction
Rachelle Crosbie is a prominent inventor based in Iowa City, IA (US). She has made significant contributions to the field of genetic research, particularly in the study of metabolic disorders. Her innovative work has led to the development of a unique transgenic model that aids in understanding the implications of sarcospan mutations.
Latest Patents
Rachelle Crosbie holds a patent for her invention titled "Sarcospan-deficient mouse as a model for clinical disorders associated with sarcospan mutations." This patent describes a transgenic knockout mouse with a homozygous disruption in its endogenous sarcospan gene. The disruption prevents the synthesis of functional sarcospan in the cells of the mouse. Notably, this mouse exhibits significantly larger epididymal fat pad deposits compared to wild-type mice, ranging from 1.4 to 6.8 times larger. The patent also outlines methods for producing this mouse and describes cells derived from it. This model can be utilized to identify therapeutic agents for treating metabolic disorders linked to the loss of wild-type sarcospan expression, such as weight gain.
Career Highlights
Rachelle Crosbie is affiliated with the University of Iowa Research Foundation, where she continues her research and development efforts. Her work has garnered attention for its potential applications in understanding and treating metabolic disorders.
Collaborations
Some of her notable coworkers include Kevin P. Campbell and Connie Lebakken, who contribute to her research endeavors.
Conclusion
Rachelle Crosbie's innovative work in genetic research, particularly her development of a sarcospan-deficient mouse model, highlights her significant contributions to the field. Her research has the potential to pave the way for new therapeutic approaches to metabolic disorders.