Company Filing History:
4 out of 123 
2 out of 832,912 Years Active: 2008-2025
Title: Qun Lu: Innovator in Alzheimer's Disease Research
Introduction
Qun Lu is a notable inventor based in Greenville, NC (US), recognized for his contributions to the field of neurodegenerative diseases. He holds a total of 6 patents, focusing primarily on methods for treating Alzheimer's disease and other related conditions. His innovative approaches aim to modulate critical signaling pathways involved in cell division and neurodegeneration.
Latest Patents
One of Qun Lu's latest patents addresses the roles of modulators of intersectin-Cdc42 signaling in Alzheimer's disease. The patent describes methods for treating Alzheimer's and other neurodegenerative, neurocognitive, and neurodevelopmental diseases. These methods involve administering compounds that modulate the activity of cell division control protein 42 (Cdc42), particularly its interaction with intersectin (ITSN). The exemplary modulator compounds include thioureas, disulfonamides of fused aromatic systems, such as benzofuran, and acyl hydrazones. Some of these compounds function as activators of Cdc42, while others serve as inhibitors. Notably, certain modulator compounds exhibit dual functionality, acting as either inhibitors or activators depending on the activation state of Cdc42 in specific disease stages or biological environments.
Career Highlights
Qun Lu has made significant strides in his career, particularly through his work at East Carolina University. His research has contributed to a deeper understanding of the molecular mechanisms underlying Alzheimer's disease, paving the way for potential therapeutic interventions.
Collaborations
Throughout his career, Qun Lu has collaborated with esteemed colleagues, including Yan-Hua Chen and Byron Aguilar. These partnerships have enhanced the scope and impact of his research in the field of neurodegenerative diseases.
Conclusion
Qun Lu's innovative work in Alzheimer's disease research exemplifies the critical role of inventors in advancing medical science. His patents and research contributions continue to inspire new approaches to treating complex neurodegenerative conditions.