Qizhi Ma

Title: Innovations of Qizhi Ma in Genetic Engineering

Introduction

Qizhi Ma is a notable inventor based in Sichuan, China. He has made significant contributions to the field of genetic engineering, particularly in the development of advanced therapeutic techniques for cancer treatment. His work focuses on enhancing the immune response against tumors, which is crucial for improving patient outcomes.

Latest Patents

Qizhi Ma holds a patent for a "Genetically engineered dual-targeting chimeric antigen receptor and use thereof." This invention addresses the up-regulated expression of PD-L1 in tumor cells and immune cells exposed to malignant serosal cavity effusion. The dual-targeting chimeric antigen receptor developed by Ma is designed to competitively bind to PD-L1, transforming an inhibition signal into an activation signal. This mechanism enhances the killing activity of T cells, while the introduction of 4-1BB promotes T cell proliferation and survival. The invention also includes a host cell expressing the dual-targeting antigen receptor, which can be utilized in preventing or treating solid tumors.

Career Highlights

Qizhi Ma is affiliated with Sichuan University, where he conducts research and develops innovative solutions in genetic engineering. His work has garnered attention for its potential impact on cancer therapies, showcasing his commitment to advancing medical science.

Collaborations

Qizhi Ma collaborates with esteemed colleagues, including Yongsheng Wang and Dan Li, who contribute to his research endeavors. Their combined expertise enhances the quality and scope of their projects, fostering a collaborative environment that drives innovation.

Conclusion

Qizhi Ma's contributions to genetic engineering, particularly through his patented innovations, highlight his role as a leading inventor in the field. His work not only advances scientific knowledge but also holds promise for improving cancer treatment strategies.