Duisburg, Germany

Pul Ümit


Average Co-Inventor Count = 2.0

ph-index = 1


Company Filing History:


Years Active: 2022

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1 patent (USPTO):Explore Patents

Title: The Innovative Work of Pul Ümit in Taste Receptor Gene Activation

Introduction

Pul Ümit is a notable inventor based in Duisburg, Germany. He has made significant contributions to the field of genetic engineering, particularly in the activation of taste receptor genes. His innovative approach utilizes the CRISPR-Cas9 technology to enhance the expression of these genes in mammalian cells.

Latest Patents

Pul Ümit holds a patent for a method titled "Activation of taste receptor genes in mammalian cells using CRISPR-Cas-9." This patent outlines a systematic approach that includes several key steps. First, it involves providing a culture of mammalian cells that contain at least one sweet receptor domain. Next, it requires designing a single-guide RNA (sgRNA) that is complementary to specific regions upstream of the translation start codon of the sweet receptor gene. The method also includes preparing a vector with an expression cassette that encompasses a modified CRISPR-Cas9 and sgRNA. The transfection of the mammalian cell culture with this vector targets the genome for the presence of a complementary DNA sequence. Finally, the transcriptional enhancement of the sweet receptor mRNA is measured using quantitative RT-PCR.

Career Highlights

Pul Ümit has dedicated his career to advancing genetic research and applications. His work at Brain Ag has positioned him as a key figure in the field of biotechnology. With a focus on taste receptor genes, he has contributed to the understanding of how these genes can be manipulated for various applications.

Collaborations

Pul Ümit collaborates with Michael Krohn, working together to push the boundaries of genetic research and innovation. Their partnership exemplifies the importance of teamwork in achieving groundbreaking results in the scientific community.

Conclusion

Pul Ümit's innovative work in activating taste receptor genes using CRISPR-Cas9 technology showcases his significant contributions to genetic engineering. His patent and ongoing research continue to pave the way for advancements in biotechnology.

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