Pilarin Elizabeth Louise Nichols

Title: Pilarin Elizabeth Louise Nichols: Innovator in Protein Formulations

Introduction

Pilarin Elizabeth Louise Nichols is a distinguished inventor based in Andover, MA (US). She has made significant contributions to the field of protein formulations, holding a total of three patents. Her innovative work focuses on enhancing the solubility and viscosity of protein formulations, which has important implications in various applications.

Latest Patents

One of her latest patents is titled "Protein formulations with reduced viscosity and uses thereof." This invention provides methods for reducing the viscosity of protein formulations by incorporating viscosity-reducing agents such as calcium chloride or magnesium chloride. Another notable patent is "Peptides as solubilizing excipients for transforming growth factor β proteins." This invention relates to compositions that include excipients or solubilizing agents for proteins. It highlights the discovery that a peptide derived from the N-terminus extension of the T266 isoform of rhBMP-2 can enhance the solubility of proteins. The methods described in this patent also include techniques for resolubilizing proteins that have precipitated.

Career Highlights

Pilarin has built a successful career at Wyeth, where she has been instrumental in advancing research and development in protein formulations. Her expertise in this area has led to significant advancements that benefit both the scientific community and the pharmaceutical industry.

Collaborations

Throughout her career, Pilarin has collaborated with notable colleagues, including Nicholas W. Warne and Paulo Jorge Loureiro. These collaborations have fostered innovation and contributed to the success of her projects.

Conclusion

Pilarin Elizabeth Louise Nichols is a remarkable inventor whose work in protein formulations has made a lasting impact. Her patents reflect her dedication to advancing scientific knowledge and improving the efficacy of protein-based applications.