Montreal, Canada

Pierre Chretien


Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 13(Granted Patents)


Company Filing History:

goldMedal1 out of 832,718 
Other
 patents

Years Active: 2001

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1 patent (USPTO):Explore Patents

Title: **Inventor Pierre Chretien: A Pioneer in HLA Typing Technology**

Introduction

Pierre Chretien, an accomplished inventor based in Montreal, Canada, has made significant contributions to the field of genetics with his innovative methods in human leukocyte antigen (HLA) typing. His unique approach to sequencing has opened new avenues for medical research and personalized medicine.

Latest Patents

Chretien holds a patent for his groundbreaking invention titled "Class I sequence-based typing of HLA-A, -B, and -C alleles by direct DNA sequencing." This patent outlines a sophisticated method for directly typing or sequencing HLA alleles from tissue samples. The innovative approach involves amplifying exons 2 and 3 of the HLA alleles in a locus-specific manner and subsequently separating and individually amplifying these segments. The amplified exons are then directly sequenced, and the resulting sequences are compared to an HLA allele database, yielding precise HLA typing crucial for various medical applications.

Career Highlights

Throughout his career, Pierre Chretien has been dedicated to advancing genetic research. His patent showcases his expertise in molecular biology, particularly in DNA sequencing techniques. His work demonstrates not only a profound understanding of genetics but also a commitment to enhancing the accuracy of HLA typing, which is vital for organ transplantation and disease association studies.

Collaborations

Chretien has collaborated with notable professionals in the field, including William H. Hildebrand and Mary Ellexson. Their collective efforts exemplify a strong partnership in research and development, enhancing the impact of their work on the scientific community and paving the way for future innovations in genetic testing.

Conclusion

Pierre Chretien's contributions to the field of HLA typing through his innovative patent have positioned him as a key figure in genetic research. His advancements not only elevate the understanding of HLA alleles but also have far-reaching implications for patient care in medical settings. As technology continues to evolve, Chretien's work remains a cornerstone of innovation within the realm of genetics.

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