Company Filing History:
Years Active: 2009-2010
Title: The Innovative Contributions of Phillipp Holliger
Introduction
Phillipp Holliger is a prominent inventor based in Cambridge, GB. He has made significant contributions to the field of molecular biology, particularly in the development of innovative methods for gene expression and enzyme selection. With a total of 2 patents, his work has garnered attention in the scientific community.
Latest Patents
Holliger's latest patents include groundbreaking inventions that enhance the capabilities of in vitro expression systems. One of his notable patents is focused on emulsion compositions, which facilitate the expression of a wide variety of gene products via eukaryotic in vitro expression. This emulsion comprises a silicone-based surfactant, a hydrophobic phase, and a hydrophilic phase, which contains compartments with a functional in vitro eukaryotic expression system.
Another significant patent is the compartmentalized self-replication method for in vitro evolution of molecular libraries. This method involves selecting an enzyme with replicase activity through a series of steps, including providing a pool of nucleic acids, subdividing them into compartments, allowing nucleic acid replication, and detecting amplification by the replicase. This innovative approach also includes methods for selecting agents that can modulate replicase activity and for identifying interacting polypeptides.
Career Highlights
Holliger is affiliated with the Medical Research Council, where he continues to push the boundaries of research in molecular biology. His work has not only advanced scientific understanding but has also opened new avenues for therapeutic applications.
Collaborations
Throughout his career, Holliger has collaborated with esteemed colleagues, including Farid Ghadassy and Jennifer Lee Ong. These partnerships have contributed to the success and impact of his research endeavors.
Conclusion
Phillipp Holliger's innovative contributions to molecular biology, particularly through his patents, highlight his role as a leading inventor in the field. His work continues to influence research and applications in gene expression and enzyme selection.