Company Filing History:
Years Active: 2023
Title: Innovations in Imaging: The Contributions of Philipp Krapf
Introduction
Philipp Krapf is an innovative inventor based in Siegburg, Germany. He has made significant contributions to the field of medical imaging, particularly in the development of probes for imaging PSMA expressing tissues. His work has the potential to enhance the diagnosis and treatment of prostate cancer and other related conditions.
Latest Patents
Krapf holds a patent for "2-alkoxy-6-[18F]fluoronicotinoyl substituted lys-c(O)-glu derivatives as efficient probes for imaging of PSMA expressing tissues." This patent outlines the identification of 6-[F]fluoro-2-alkoxynicotinoyl substituted Lys-C(O)-Glu derivatives as efficient imaging probes. These probes have shown superior performance compared to other known PSMA specific ligands, such as [F]DCFPyL and [Ga]HBED-CC-PSMA. The 2-alkoxy derivative demonstrated higher cellular uptake values in PSMA expressing prostate tumor cells, while the 4-alkoxy substituted derivative exhibited significantly lower uptake. In vivo PET studies have confirmed the excellent visualization capabilities of these probes, making them valuable tools in clinical settings.
Career Highlights
Krapf's career is marked by his dedication to advancing medical imaging technologies. His innovative approach has led to the development of probes that are not only effective but also easily accessible for clinical use. The 2-methoxy derivative he developed has shown exceptional clinical efficiency in detecting small prostate cancer lesions, even those that are not visible with current gold standard methods. This advancement represents a significant leap forward in the diagnosis of recurrent prostate cancer.
Collaborations
Philipp Krapf has collaborated with notable colleagues, including Bernd Neumaier and Boris Zlatopolskiy. These collaborations have further enriched his research and contributed to the successful development of his patented technologies.
Conclusion
Philipp Krapf's contributions to the field of medical imaging through his innovative patents have the potential to revolutionize the diagnosis and treatment of prostate cancer and other related conditions. His work exemplifies the importance of innovation in advancing healthcare technologies.