Philipp Koch

Title: Innovations of Inventor Philipp Koch

Introduction

Philipp Koch is a notable inventor based in Basel, Switzerland. He has made significant contributions to the field of biochemistry, particularly in the synthesis of non-canonical amino acids. With a total of 3 patents, his work has garnered attention in both academic and industrial circles.

Latest Patents

Koch's latest patents focus on methods and enzyme catalysts for the synthesis of β-substituted tryptophan compounds. The disclosed methods involve combining an unsubstituted or substituted indole, a β-substituted serine, and a tryptophan synthase β-subunit (TrpB). The resulting mixture is maintained under specific conditions to form the β-substituted tryptophan. Notably, the TrpB contains at least one amino acid mutation that promotes the formation of an amino-acrylate intermediate. His patents also describe new TrpB variants and new β-substituted tryptophan analogs.

Career Highlights

Philipp Koch is affiliated with the California Institute of Technology, where he continues to advance his research in biochemistry. His innovative approaches have positioned him as a key figure in the development of new methodologies for amino acid synthesis.

Collaborations

Koch has collaborated with esteemed colleagues such as Christina E Boville and Sabine Brinkmann-Chen. Their joint efforts have further enhanced the impact of his research in the scientific community.

Conclusion

Philipp Koch's contributions to the field of biochemistry through his patents and collaborations highlight his role as an influential inventor. His work on non-canonical amino acids continues to pave the way for advancements in biochemical research and applications.