Petr Pompach

Title: Petr Pompach: Innovator in Surface Modification Techniques

Introduction

Petr Pompach is a notable inventor based in Mratin, Czech Republic. He has made significant contributions to the field of surface modification, particularly in the context of mass spectrometry and immunochemical assays. With a total of 2 patents, his work focuses on enhancing the efficiency of analyte preconcentration from complex samples.

Latest Patents

Pompach's latest patents include a method of surface modification by proteins for analyte preconcentration for desorption-ionization mass spectrometry techniques and for immunochemical assays. This innovative method involves the modification of solid substrates with proteins to facilitate efficient surface preconcentration of analytes. The process utilizes electronebulization, or electrospraying, of protein solutions, which can include enzymes, lectins, or antibodies. The resulting charged electrospray is dried in real time, allowing for a stable binding of desolvated ions to the surface. This modified surface can then be employed for selective interactions with affinity partners, enabling preconcentration or enzymatic modifications followed by analysis.

Another significant patent by Pompach is a method of surface modification for analyzing phosphorylated peptides. This technique modifies solid substrates to enhance the preconcentration of phosphorylated peptides from complex mixtures prior to detection. The method employs ambient ion landing and electronebulization of organometallic compounds, particularly those related to zirconium, hafnium, and titanium. The generated charged electrospray forms a stable oxide layer on the surface, which is effective for phosphopeptide enrichment before desorption/ionization mass spectrometry.

Career Highlights

Petr Pompach has worked at the Institute of Microbiology AS CR, v.v.i., where he has contributed to various research projects. His expertise in surface modification techniques has positioned him as a key figure in the field.

Collaborations

Pompach has collaborated with notable colleagues, including Michael Volny and Petr Novak, enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Petr Pompach's innovative work in surface modification techniques has significantly advanced the fields of mass spectrometry and immunochemical assays. His patents reflect a deep understanding of the complexities involved in analyte preconcentration, showcasing his role as a leading inventor in this specialized area.