Company Filing History:
Years Active: 2016
Title: Innovations in RNA Probes by Peter Joseph Crisalli
Introduction
Peter Joseph Crisalli is an accomplished inventor based in Portola Valley, California. He has made significant contributions to the field of molecular biology, particularly in the area of RNA structure and its applications. His innovative work has led to the development of methods and probes that enhance our understanding of RNA.
Latest Patents
Crisalli holds a patent titled "Probes of RNA structure and methods for using the same." This patent provides methods for obtaining structural data from RNA in a sample, along with RNA probes designed for this purpose. The invention includes methods for reversibly modifying RNA, both in vitro and in vivo, and introduces reversible probes that feature aryl or heteroaryl rings with specific reactive groups. Additionally, the patent outlines methods for comparing RNA structural data obtained from in vitro and in vivo studies, as well as methods for diagnosing cellular proliferative diseases by probing HOTAIR RNA. The invention also encompasses various compositions, including probes and kits, that are useful in these methods.
Career Highlights
Crisalli is affiliated with Leland Stanford Junior University, where he continues to advance research in RNA biology. His work has garnered attention for its potential applications in diagnostics and therapeutic strategies.
Collaborations
Crisalli has collaborated with notable researchers such as Robert Carl Spitale and Howard Yuan-Hao Chang. These collaborations have further enriched his research and contributed to the advancement of RNA probe technology.
Conclusion
Peter Joseph Crisalli's innovative work in RNA probes represents a significant advancement in molecular biology. His contributions have the potential to impact diagnostics and therapeutic approaches in the medical field.