Paul T Kim

Title: Paul T Kim: Innovator in Cryo-Electron Microscopy

Introduction

Paul T Kim is a prominent inventor based in San Francisco, California. He has made significant contributions to the field of cryo-electron microscopy, particularly through his innovative methods that enhance data collection processes. His work is vital for advancing research in structural biology.

Latest Patents

Paul T Kim holds a patent for a method titled "Automating cryo-electron microscopy data collection." This invention focuses on the automated control of a microscope in cryogenic electron microscopy (cryo-EM). The method allows for the collection of high-magnification micrographs of particles suspended in vitreous ice. The process is conducted during an active data collection session and utilizes a pipeline that includes a set of models. This pipeline evaluates various collection locations to determine whether to continue at the current grid square or move to a new one. The evaluation is based on quality scores derived from pretrained models and machine learning-based active learning. Consequently, control information is provided to automatically guide the microscope to the next target for data collection.

Career Highlights

Paul T Kim is associated with the New York Structural Biology Center, where he applies his expertise in cryo-electron microscopy. His innovative approach has positioned him as a key figure in the field, contributing to advancements in understanding biological structures at the molecular level.

Collaborations

One of his notable collaborators is Tristan Bepler, with whom he has worked closely on various projects related to cryo-electron microscopy. Their partnership has fostered significant advancements in the methodologies used in this area of research.

Conclusion

Paul T Kim's contributions to cryo-electron microscopy through his innovative patent and collaborative efforts highlight his importance in the field of structural biology. His work continues to pave the way for future advancements in microscopy techniques.