Company Filing History:
2 out of 932 
1 out of 5 Years Active: 1996-2001
Title: The Innovative Contributions of Paul Goldberg
Introduction
Paul Goldberg is a notable inventor based in Vancouver, Canada. He has made significant contributions to the field of genetics and neurobiology, particularly in relation to Huntington's disease. With a total of 2 patents, his work has the potential to influence therapeutic approaches for this challenging condition.
Latest Patents
Goldberg's latest patents focus on apoptosis modulators that interact with the Huntington's disease gene. He identified a family of proteins, including a specific human protein designated as HIP1, which interacts differently with the gene product of a normal and an expanded HD gene. His research indicates that the expression of the HIP1 protein is enriched in the brain and suggests a potential apoptotic function. This understanding of the role of huntingtin and HIP1 in the pathology of Huntington's disease opens up several therapeutic possibilities. For instance, gene therapy could be employed to enhance the expression of normal huntingtin or the HIP-binding region of huntingtin, potentially providing therapeutic benefits.
Another significant patent involves the process for isolating genes and identifying the gene causative of Huntington's disease. The underlying genetic defect has been mapped to chromosomal band 4p16.3, with refined localization identifying two distinct candidate regions. His work has led to the mapping of several clones within the minimal region containing the HD gene, which are particularly useful in detecting changes in this portion of the gene in HD patients.
Career Highlights
Throughout his career, Paul Goldberg has worked with esteemed institutions such as the University of British Columbia and HSC Research and Development Limited. His research has contributed to a deeper understanding of genetic factors in neurodegenerative diseases.
Collaborations
Goldberg has collaborated with notable colleagues, including Michael R. Hayden and Michael Kalchman, further enhancing the impact of his research in the scientific community.
Conclusion
Paul Goldberg's innovative work in the field of genetics, particularly concerning Huntington's disease, showcases his dedication to advancing medical science. His patents and research have the potential to pave the way for new therapeutic strategies, ultimately benefiting those affected by this condition.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.