Company Filing History:
Years Active: 2023-2025
Title: The Innovative Contributions of Patrick G Dougherty
Introduction
Patrick G Dougherty is a notable inventor based in Columbus, OH (US). He has made significant contributions to the field of biochemistry, particularly in the development of peptide-based inhibitors. With a total of 3 patents, Dougherty's work has the potential to impact various therapeutic applications.
Latest Patents
Dougherty's latest patents include innovative peptides designed to inhibit specific protein interactions. One of his notable inventions is the "Peptidyl inhibitors of calcineurin-NFAT interaction." This patent describes peptides and peptide conjugates that comprise calcineurin binding motifs (CNBM) which inhibit the interaction between calcineurin and NFAT. The peptides may include a hydrophobic, non-peptidic moiety that interacts with the hydrophobic pocket on a calcineurin protein, along with a specific amino acid sequence that can be modified.
Another significant patent is the "Cyclic peptidyl inhibitors of CAL-PDZ binding domain." This invention involves peptides that contain a cyclic cell-penetrating peptide sequence and a CAL-PDZ binding sequence. The design allows for improved delivery and binding selectivity of the CAL-PDZ binding sequence to its target domain, enhancing its potential therapeutic efficacy.
Career Highlights
Dougherty is associated with the Ohio State Innovation Foundation, where he continues to advance his research and development efforts. His work is characterized by a strong focus on peptide chemistry and its applications in medicine.
Collaborations
Dougherty has collaborated with esteemed colleagues such as Dehua Pei and John W Christman. These partnerships have likely contributed to the innovative nature of his research and the successful development of his patents.
Conclusion
Patrick G Dougherty's contributions to peptide-based inhibitors demonstrate his commitment to advancing biochemistry and therapeutic solutions. His innovative patents reflect a deep understanding of protein interactions and their implications in medicine.