Company Filing History:
11 out of 5,194 
1 out of 832,880 Years Active: 1994-2000
Title: The Innovative Contributions of Patricia A. Spears
Introduction
Patricia A. Spears is a notable inventor based in Raleigh, NC (US), recognized for her significant contributions to the field of diagnostics. With a total of 12 patents to her name, she has made remarkable advancements in the detection of infectious diseases.
Latest Patents
One of her latest patents focuses on the "Detection of M. tuberculosis complex via reverse transcriptase SDA." This invention provides primers that can be utilized for M. tuberculosis complex-specific detection of .alpha.-antigen DNA in diagnostic assays performed on clinical specimens. The primers and probes can also be employed in a reverse transcriptase-mediated amplification system for M. tuberculosis complex .alpha.-antigen mRNA. This assay offers a means to determine the viability of M. tuberculosis complex organisms in clinical specimens or when grown in culture. Additionally, she has developed methods for the detection of amplification products using radiolabeled probes through chemiluminescent assays or fluorescence polarization analysis. Another significant patent involves the "Amplification and detection of chlamydia trachomatis nucleic acids," which describes amplification primers useful for species-specific detection of a target sequence in the cryptic plasmid of C. trachomatis.
Career Highlights
Throughout her career, Patricia has worked with prominent companies, including Becton Dickinson and Company Limited. Her work has significantly impacted the field of medical diagnostics, particularly in the detection of bacterial infections.
Collaborations
Patricia has collaborated with esteemed colleagues such as Daryl D. Shank and James G. Nadeau, contributing to her innovative research and development efforts.
Conclusion
Patricia A. Spears exemplifies the spirit of innovation in the field of diagnostics, with her patents paving the way for improved detection methods for infectious diseases. Her contributions continue to influence the medical community and enhance public health outcomes.