Company Filing History:
Years Active: 2013
Title: Innovations of Pandurang Vilasrao Chouthaiwale
Introduction
Pandurang Vilasrao Chouthaiwale is a notable inventor based in Pune, India. He has made significant contributions to the field of chemistry, particularly in the development of innovative processes for synthesizing complex organic compounds. With a total of 2 patents to his name, Chouthaiwale's work has implications in various applications, including pharmaceuticals.
Latest Patents
Chouthaiwale's latest patents include a process for the aziridination of olefins. This process utilizes a combination of NaIO4, alkali metal bromide, H, and Chloramine-T in the presence of a dipolar aprotic solvent under ambient conditions to obtain aziridines. Another significant patent is for the preparation of β-amino alcohol. This high-yielding enantioselective synthesis involves the bioactive (S)—N-(5-chlorothiophene-2-sulfonyl)-β,β-diethylalaniol, which acts as a Notch-1-sparing γ-secretase inhibitor metabolite. The synthesis starts from readily available 3-pentanone and includes key steps such as proline-catalyzed α-aminooxylation and α-amination of aldehyde, achieving an overall yield of 50-75% and 90-99% enantiomeric excess.
Career Highlights
Chouthaiwale is affiliated with the Council of Scientific and Industrial Research, where he continues to engage in research and development. His work has garnered attention for its innovative approaches and practical applications in the field of organic chemistry.
Collaborations
Chouthaiwale has collaborated with notable coworkers, including Gurunath Mallappa Suryavanshi and Arumugam Sudalai. These collaborations have contributed to the advancement of his research and the successful development of his patented processes.
Conclusion
Pandurang Vilasrao Chouthaiwale's contributions to the field of chemistry through his innovative patents highlight his role as a significant inventor. His work not only advances scientific knowledge but also has practical implications in various industries.