Company Filing History:
Years Active: 1992-1993
Title: Innovations by Pamela C. Esmon
Introduction
Pamela C. Esmon is a notable inventor based in Richmond, CA (US). She has made significant contributions to the field of biochemistry, particularly in the development of methods for detecting and evaluating proteins. With a total of three patents to her name, her work has implications in medical diagnostics and therapeutic development.
Latest Patents
Esmon's latest patents include a method of detecting proteolytically modified antithrombin and a method for evaluating immunogenicity. The first patent describes an indirect method for detecting elastase-modified or cleaved antithrombin (ATx) in the presence of intact antithrombin (AT-III). This inventive method utilizes a modified ELISA that incorporates a detergent to alter the intact AT-III. Cleaved AT-III is generated in human plasma, followed by an ELISA performed in the presence of the detergent. The second patent outlines a method for evaluating the potential immunogenicity of a protein derived from recombinant DNA technology. This method involves injecting an animal with the recombinant protein and isolating antiserum from the animal. The antiserum is then depleted of antibodies to a reference protein by adsorbing it against the reference protein. The adsorbed antiserum is subsequently blotted against the recombinant protein to determine if any antibodies were produced that recognize the recombinant protein but did not recognize the plasma-derived protein during adsorption.
Career Highlights
Pamela C. Esmon is currently employed at Miles Inc., where she continues to innovate and contribute to advancements in her field. Her work has garnered attention for its potential applications in improving diagnostic techniques and understanding protein interactions.
Collaborations
Esmon collaborates with several talented individuals, including Michael A. Fournel and Emma Yee. These partnerships enhance her research and contribute to the success of her projects.
Conclusion
Pamela C. Esmon's innovative work in the field of biochemistry exemplifies the impact of dedicated inventors on medical science. Her patents reflect a commitment to advancing diagnostic methods and understanding protein behavior, which can lead to significant improvements in healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.