Company Filing History:
Years Active: 1991
Title: The Innovative Contributions of Padmaker V Kulkarni
Introduction
Padmaker V Kulkarni is a notable inventor based in Dallas, TX (US). He has made significant contributions to the field of immunoassay methods, particularly in the detection and measurement of analytes in serum. His work has implications for medical diagnostics and has the potential to improve patient care.
Latest Patents
Kulkarni holds a patent for a "Two site cross-reaction immunometric sandwich assay method." This innovative method is designed for the detection and measurement of an analyte, such as creatine phospho-kinase-MB, in serum. The method involves the selection of two different antibodies, each specific to a different analyte but capable of cross-reacting with the analyte of interest. The first antibody is reacted with the unknown sample using a solid-phase to bind the first antibody. The separation of the solid and liquid portions of the first reaction is accomplished, followed by the reaction of the solid portion with a tagged second antibody. The solid and liquid portions of the second reaction are then separated, and the solid portion is tested for the tag as an indication of the presence of the analyte. This method is particularly relevant for testing creatine phospho-kinase-MB in human serum, utilizing cross-reacting antibodies to creatine phospho-kinase-BB and creatine phospho-kinase-MM.
Career Highlights
Kulkarni is associated with International Immunoassay Laboratories, Inc., where he applies his expertise in immunoassay development. His innovative approach has led to advancements in diagnostic methods, enhancing the accuracy and efficiency of medical testing.
Collaborations
He has collaborated with notable coworkers such as Vipin D Shah and Quirinus Ronnie Miranda, contributing to the advancement of immunoassay technologies.
Conclusion
Padmaker V Kulkarni's contributions to the field of immunoassays exemplify the impact of innovative thinking in medical diagnostics. His patented methods are paving the way for improved detection and measurement of critical analytes, ultimately benefiting patient care.