Octavio Ramilo

Title: Octavio Ramilo: Innovator in Respiratory Syncytial Virus Research

Introduction

Octavio Ramilo is a prominent inventor based in Columbus, OH (US). He has made significant contributions to the field of virology, particularly in the study of respiratory syncytial virus (RSV). His innovative work has led to advancements in understanding and combating this viral infection.

Latest Patents

Ramilo holds a patent titled "Respiratory syncytial virus having altered NS1 protein function and related materials and methods." This patent describes compositions, methods, and uses for RSV and immunogenic compositions. The invention focuses on RSV with a mutated NS1 protein, which uncouples the protein's replication and type I interferon antagonist functions. This uncoupling can produce virions that induce a strong, long-lasting innate immune response while maintaining their ability to replicate in vitro. The patent also outlines methods for amplifying RSV in host cells, leading to the formulation of immunogenic compositions, including vaccines.

Career Highlights

Throughout his career, Ramilo has worked at notable institutions, including the Research Institute at Nationwide Children's Hospital and the University of South Florida. His research has been pivotal in advancing the understanding of RSV and developing potential treatments and vaccines.

Collaborations

Ramilo has collaborated with esteemed colleagues, including Mark Edward Peeples and Michael Nan-hao Teng. These partnerships have further enriched his research and contributed to the scientific community's knowledge of RSV.

Conclusion

Octavio Ramilo's innovative work in the field of respiratory syncytial virus research has led to significant advancements in virology. His contributions continue to impact the development of effective treatments and vaccines for this viral infection.