Norio Ohnuma

Title: Inventor Norio Ohnuma and His Significant Contribution to Peptide Technology

Introduction

Norio Ohnuma, a distinguished inventor based in Osaka, Japan, has made noteworthy contributions to the field of biotechnology. With his extensive background and expertise, he holds a significant patent that showcases innovative advancements in peptide technology.

Latest Patents

Ohnuma's most prominent patent is for the precursor of a C-terminal amidated calcitonin. This invention is represented by the general formula P-X-Gly-Y.sub.n, where P signifies a peptide residue. The innovation allows for the C-terminal of the amino acid residue X (on the Gly side) to be converted in vivo to a --CONH.sub.2 group. The structure also includes Gly as a glycine residue, Y as a basic amino acid residue, and n as an integer from 2 to 4. A further amino acid residue, other than Y, or a peptide residue may also be attached to Y.sub.n. This precursor is produced using genetic engineering technology and exhibits in vivo physiological activity akin to the C-terminal amidated peptide.

Career Highlights

Norio Ohnuma works for Suntory Limited, a well-respected company known for its commitment to research and development in the field of biotechnology. His work there has garnered significant attention, especially regarding the development of peptides and their physiological implications.

Collaborations

Throughout his career, Ohnuma has collaborated with esteemed colleagues like Shoji Tanaka and Kazuhiro Ohsuye. These partnerships within Suntory Limited have furthered advancements in peptide technology, benefiting the scientific community and paving the way for future research.

Conclusion

Norio Ohnuma stands out as a key inventor in peptide technology, with his notable patent reflecting the innovative spirit of his work. His contributions not only enhance our understanding of biochemical processes but also hold potential applications in medicine and biotechnology.