Title: Norbert Basler - Innovator in Nucleic Acid Amplification
Introduction
Norbert Basler is an inventor based in Munich, Germany. He is currently associated with Agct GmbH, where he focuses on advancements in the field of nucleic acid amplification. Although he does not hold any granted patents, his contributions to the field are noteworthy.
Latest Patent Applications
Norbert Basler's notable patent application is titled "Method for Selective Amplification of Nucleic Acids and Kit for Performing the Same." This method discloses a technique for detecting the amplification of nucleic acids by utilizing a predefined nucleic acid chain, known as the target sequence. The process involves the use of a target-sequence-specific activator oligonucleotide, which facilitates the separation of newly synthesized complementary primer elongation products through strand displacement. This allows a new primer oligonucleotide to attach to the respective strand of the template, initiating a new primer elongation reaction. The resulting primer elongation products serve as templates, leading to an exponentially proceeding amplification reaction. The method ensures selective amplification by employing variants of the first and second primers and the activator oligonucleotide that differ from the target sequence by at least one nucleotide.
Conclusion
Norbert Basler's work in nucleic acid amplification represents a significant contribution to the field, showcasing innovative methods that enhance detection capabilities. His ongoing research at Agct GmbH continues to push the boundaries of scientific understanding in this area.