Company Filing History:
Years Active: 2025
Title: Ningning He: Innovator in Immunomodulatory Hydrogel Technology
Introduction
Ningning He is a prominent inventor based in Tianjin, China. He has made significant contributions to the field of biomedical engineering, particularly in the development of innovative materials for medical applications. His work focuses on creating advanced hydrogels that can modulate immune responses, which is crucial for various therapeutic applications.
Latest Patents
Ningning He holds a patent for an "Immunomodulatory hydrogel and preparation method thereof." This innovative hydrogel is prepared using methoxy polyethylene glycol amine (mPEG-NH) as an initiator. The mPEG-NH reacts with L-tyrosine-N-carboxyanhydrides (L-Tyr-NCAs) to form a methoxy polyethylene glycol-poly L-tyrosine (PETyr) block copolymer. The PETyr is then reacted with tyrosinase to create an oxidized methoxy polyethylene glycol-poly L-tyrosine copolymer (PETO). By co-dissolving the PETO with octyl itaconate nanomicelles (ITA8) in a disperse medium, an itaconic acid-loaded immunomodulatory hydrogel (PETO-ITA8) is obtained. This patent highlights his innovative approach to enhancing immune modulation through advanced materials.
Career Highlights
Ningning He is affiliated with the Institute of Radiation Medicine, Chinese Academy of Medical Sciences, and Peking Union Medical College. His work at these prestigious institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research in immunology and material science.
Collaborations
Ningning He has worked alongside notable colleagues, including Huijuan Song and Qiang Liu. Their collaborative efforts have further advanced the research and development of immunomodulatory materials, enhancing the potential for new therapeutic applications.
Conclusion
Ningning He is a key figure in the field of immunomodulatory hydrogel technology, with a focus on innovative solutions for medical applications. His contributions through patents and collaborations continue to shape the future of biomedical engineering.