Nanyan Zhang

Title: Nanyan Zhang: Innovator in Bioengineering Platelets

Introduction

Nanyan Zhang is a prominent inventor based in Wauwatosa, WI (US). He has made significant contributions to the field of bioengineering, particularly in the development of designer platelets. His innovative work focuses on utilizing gene editing and stem cell methodologies to create cells with specific platelet alloantigens.

Latest Patents

Nanyan Zhang holds a patent for a groundbreaking method titled "Method to bioengineer designer platelets using gene editing and stem cell methodologies." This patent outlines methods for creating cells that express specific platelet alloantigens by combining gene editing techniques with cell culture differentiation or expansion techniques. The process involves transfecting pluripotent cells with a plasmid that encodes guide RNAs targeting a platelet alloantigen target locus and a nuclease, along with an HDR repair oligo. The resulting cells can then be cultured to expand their numbers or to create a differentiated cell type of interest. He has 1 patent to his name.

Career Highlights

Nanyan Zhang is affiliated with the Versiti Blood Research Institute Foundation, Inc., where he continues to advance his research in platelet bioengineering. His work is pivotal in enhancing the understanding and application of gene editing in medical science.

Collaborations

Nanyan collaborates with esteemed colleagues, including Peter J. Newman and Sridhar Rao, who contribute to his research endeavors and help drive innovation in the field.

Conclusion

Nanyan Zhang's contributions to bioengineering and gene editing are noteworthy, as he continues to push the boundaries of science and technology. His innovative methods for creating designer platelets hold promise for future advancements in medical treatments.