Company Filing History:
Years Active: 2000-2001
Title: Nandini Katre: Innovator in Liposomal Drug Delivery
Introduction
Nandini Katre is a prominent inventor based in Solana Beach, California. She has made significant contributions to the field of drug delivery systems, particularly through her innovative work on multivesicular liposomes. With a total of two patents to her name, Katre's inventions focus on enhancing the bioavailability and controlled release of biologically active agents.
Latest Patents
Katre's latest patents include "High and low load formulations of IGF-I in multivesicular liposomes" and "Modulation of drug loading in multivesicular liposomes." The first patent discloses multivesicular liposomes containing IGF-I with substantially full bioavailability. The loading of IGF-I into the liposomes is modulated by adjusting the osmolarity of the aqueous component used during the manufacturing process. This innovative approach allows for controlled release rates of the active agent by incorporating long chain amphipathic lipids into the lipid component. The second patent outlines a method for making liposomes, where the osmolarity of the aqueous component is adjusted to modulate the loading of active agents. This method also emphasizes the importance of long chain amphipathic lipids in controlling release rates and encapsulation efficiency.
Career Highlights
Throughout her career, Katre has worked with notable companies, including Skye Pharma, Inc. Her experience in the pharmaceutical industry has equipped her with the knowledge and skills necessary to develop advanced drug delivery systems.
Collaborations
Katre has collaborated with esteemed colleagues such as Qiang Ye and Mantripragada Bhima Sankaram. These collaborations have further enriched her research and development efforts in the field of liposomal formulations.
Conclusion
Nandini Katre's innovative work in liposomal drug delivery systems has the potential to significantly impact the pharmaceutical industry. Her patents reflect a deep understanding of drug formulation and release mechanisms, paving the way for future advancements in this critical area of research.