Company Filing History:
Years Active: 1998-2001
Title: Innovations by Nancy G Wehner
Introduction
Nancy G Wehner is a notable inventor based in Fremont, CA, who has made significant contributions to the field of immunology. With a total of 2 patents to her name, her work focuses on enhancing the detection of T-cell reactivity, which is crucial for understanding immune responses.
Latest Patents
One of her latest patents is a method for monitoring T cell reactivity. This invention provides a highly sensitive assay for the detection of T-cells reactive to an antigen by detecting a soluble factor whose secretion is induced by stimulation of the T-cell by the antigen. The assay includes an antigen-driven proliferation of specific T cells prior to restimulation with irradiated antigen presenting cells (APCs) and antigen. In exemplary embodiments, the assay is used to enhance the detection limits of human peripheral blood mononuclear cells (PBMCs) secreting interferon-γ (IFN-γ) and interleukin-2 (IL-2). The assay can be performed on previously frozen PBMCs, providing greater convenience in sample processing, multiple use of a single sample as an internal standard, and simultaneous analysis of samples collected at different time points.
Career Highlights
Nancy Wehner is currently associated with Anergen, Inc., where she continues to innovate in her field. Her work has been instrumental in advancing methodologies that improve the understanding of immune responses.
Collaborations
Some of her notable coworkers include Edward G Spack and Michael A McCutcheon, who have collaborated with her on various projects.
Conclusion
Nancy G Wehner's contributions to the field of immunology through her innovative patents demonstrate her commitment to advancing scientific knowledge and improving diagnostic methods. Her work continues to have a significant impact on the understanding of T-cell reactivity.